A corpulent, corrupt Twi'lek Senator from Ryloth, Orn Free Taa was disliked on his homeworld for enriching himself on Coruscant and enmeshing himself in politics, becoming a leading power broker in the Senate. Free Taa was one of the Republic's leading Loyalists and a strong backer of the military, but his indulgences made him a symbol of everything the Separatists considered rotten about the Republic.
The freedom fighter Cham Syndulla arose on Ryloth during the Clone Wars, after the Separatists invaded his homeworld. A dedicated fighter with no tolerance for corruption or dishonesty, Syndulla forged an alliance with Mace Windu that brought liberty to his fellow Twi'leks.
A Twi'lek child who lived on the planet Ryloth during the Clone Wars, Numa escaped being captured by the Separatist droid army by hiding in tunnels beneath the town of Nabat. Two clone troopers from Ghost Company -- Boil and Waxer -- discovered Numa while on a recon mission. She showed them the tunnels, which Obi-Wan Kenobi then used to free the Twi'lek prisoners and defeat the town's Separatist occupiers.
Ryloth is the principal planet in the Ryloth system located in the Outer Rim near Tatooine. It is home to the Twi'leks, a humanoid species with two large, fleshy head-tails growing from their skulls. The Twi'leks call these prehensile appendages lekku and can communicate through subtle lekku gestures, although they also speak Twi'leki. During the Clone Wars, scheming Separatist warlords blockaded and invaded Ryloth, hoping to steal its riches.